 |
|
May 25, 2012
Mark Clayton: Is Hillary's State Dept. hacking Al Qaeda? Not quite
Erika Bolstad: Temple cancels Wasserman Schultz speech
The Kosher Gourmet by Ethel G. Hofman: The former president of the International Association of Culinary Professionals, whose members included the likes of Julia Child, is back with contemporary Shavous cuisine: Ruby Fruit Soup, Sweet Noodle Kugel with Cheese, Key Lime Curd, Calsone Casserole Frittata with Wild Mushrooms, Sun-dried tomatoes and Olives, Baked Tilapia with Pepper Cheese Cream and Brown Sugar Shortbread
May 24, 2012
Jeff Jacoby: The peace process battered Israel's reputation
Michael Muskal: 'Pro-choice' position hits record low, according to poll
Chris Farrell: Are We in a Tech Bubble?
The Kosher Gourmet by Penelope Wall: PHILLY CHEESE STEAKS --- hold the steak!
May 23, 2012
Tony Pugh: More private colleges offering tuition discounts
Mary Beth Franklin: How to Choose the Right Annuity for You
Tina Susman: The wig wasn't enough: Man gets 13 years for posing as his dead mom
The Kosher Gourmet by Emma Christensen:A simple way to do fish right
May 22, 2012
Warren Richey: Can US group challenge overseas surveillance act? Supreme Court to decide
Thomas M. Anderson: Walking Away From a Mortgage
The Kosher Gourmet by Megan Gordon: Enjoy a celebration of the most rich and layered flavors: Black bean, sweet potato and quinoa chili
May 21, 2012
Mark Clayton: Cybersecurity: How US utilities passed up chance to protect their networks
Howard LaFranchi: NATO summit: Who will foot the bill for long-term Afghanistan security?
Chris Farrell : Earn Dividends in Emerging Markets with This WisdomTree ETF
Stephen Whiteside, Ph.D. : Mayo Clinic Medical Edge: Social anxiety disorder --- or just shy?
Guy Jackson : Victim's father regrets death of Lockerbie bomber
The Kosher Gourmet by Mario Batali: Famed chef's veal shoulder farsumagru: A festive meat course for late spring
May 18, 2012
Rabbi Berel Wein: Striving: The People of the Book's Book for (All of) the People
Steven Goldberg: 5 Great Stock Picks and the Exchange-Traded Fund that Owns Them
Mary Pickett, M.D.: Ask the Harvard Experts: Don't be forced into gluten-free lifestyle based merely on a doctor's false-positive test
The Kosher Gourmet by Carolyn Malcoun: DIY healthy lunchbox treats: HOMEMADE FRUIT BARS for kids and brown-bagging adults alike
May 17, 2012
Warren Richey: Teacher fired for being unwed and pregnant can sue religious school, court rules
Josh Mitnick: Netanyahu's 'centrist' coalition is already proving it's anything but
Steven Goldberg: Earn Dividends in Emerging Markets with This WisdomTree ETF
Amina Khan: Research links coffee to lower death rates
The Kosher Gourmet by Faith Duran : Cheesy Potato Breakfast Casserole with Cheddar and Sun-Dried Tomatoes
May 16, 2012
Carmen Terzic, M.D., Ph.D. : Mayo Clinic Medical Edge: A variety of exercises can help improve balance
Melissa Healy: National strategy on Alzheimer's disease aims to halt it by 2025
The Kosher Gourmet by Joyce White : GOODNESS GRACIOUS: GREENS! 4 winning recipes that are no longer just for down-home folks (Includes expert tips & techniques)
May 15, 2012
Kristen Chick: Obama administration resumes arms sales to Bahrain despite serious unresolved human rights issues. Activists feel abandoned
Pat Mertz Esswein: Homes are now affordable again and mortgage rates are low. What you need to know before you buy
Kathy Kristof: Our Practical Investor Fights Inflation with These 6 Investments
Sue Hubbard, M.D.: The Kid's Doctor: Lactose intolerant young child? Check again
The Kosher Gourmet by Kathy Hunt: Spread a Little Excitement with EXOTIC CONDIMENTS (4 RECIPES)
May 14, 2012
Lisa Gerstner: How to Protect Your Identity, Finances If You Lose Your Phone
Harvard Health Letters: Heart disease and dementia
The Kosher Gourmet by Megan Gordon: MANGO COCONUT OAT MORNING MUFFINS are a bright but hearty delight
May 11, 2012
Jessica L. Anderson: Get the Best Deal on a Used Car
Jett Stone: Forget face-lifts and fake knees. Scientists have seen the fountain of youth --- and it's broccoli
The Kosher Gourmet by Chef Mario Batali: The famed chef's vegetable dish that tastes true to the season: FAVAS AND SUGAR SNAP PEAS WITH POTATOES AND TARRAGON
May 10, 2012
Sergei L. Loiko: Putin sends warning to U.S., NATO in Victory Day speech at Red Square
Mary Rourke: How being a 'mentch' got Vidal Sasoon his start and fighting in Israel's War of Independence provided him with confidence and a strong sense of his own identity
Jeff Bertolucci: Get Home Phone Service for Less Than $10 a Month
The Kosher Gourmet by Betty Rosbottom: Gleaming with its golden, crimson, and snowy white hues, this silken smooth and creamy STRAWBERRY ORANGE TRIFLE looks impressive, but is easy to prepare
May 9, 2012
Sharon Palmer, R.D. How you can reduce your risk -- or delay -- chronic diseases associated with aging
|
| |
Jewish World Review
Researchers discover areas in human genome that may help find causes of certain disorders
By
Thomas H. Maugh II
http://www.JewishWorldReview.com | (MCT)
Researchers have found more than 15 million places in the human genome where the genetic code differs from person to person, providing a catalog of hotspots for genetic change that should speed the search for genetic causes of such complex disorders as diabetes, Alzheimer's and heart disease.
Only 10 years after scientists laboriously unraveled the first sequence of a human genome, an international team said Wednesday they have sequenced the bulk of the genomes from more than 800 people in the pilot stage of the so-called 1000 Genomes Project that aims to complete 2,500 sequences by the end of 2012 at a cost of $120 million.
More than 99 percent of the human genome is identical in all of the Earth's nearly 7 billion inhabitants; it is in that minuscule 1 percent left over that individual physical characteristics, such as eye color, height, and disease propensity lie hidden. The research team reported that it has now identified 95 percent of the individual places in the genome where such information is stored and is well on their way to discovering all of them.
The key to this progress is the development of powerful new DNA-sequencing machines that enable researchers to accomplish in hours feats that used to require months or even years at a fraction of the cost.
"In the last 10 years, DNA sequencing technology has advanced dramatically so that it becomes feasible to systematically sequence many people to find genetic variants and build a catalog which we can use as a basis for investigations into disease genetics and which variants may be functional," Dr. Richard Durbin of the Wellcome Trust Sanger Institute in England, co-chair of the project, said at a news conference.
The human genetic blueprint, or genome, is composed of an estimated 20,000 to 25,000 genes encoded in a chain of about 3.1 billion individual chemicals called bases. The initial effort to decode, or sequence, the genome of one individual took more than 10 years and cost more than $3 billion.
But researchers reported Wednesday in the journal Nature that their pilot project now includes the entire genomes of 179 people of European, West African and East Asian ancestry as well as the gene-coding regions of another 697 people. The resulting information on more than 4.5 trillion bases of DNA sequences is enough to fill 400,000 books the size of the New York City telephone directory.
The results so far have produced a number of surprises.
Among the individuals whose genomes were fully sequenced were two families of father, mother and daughter. The team found that each daughter had about 60 genetic variants that were not inherited from either parent and apparently arose on their own.
The team also discovered that, on average, each person carries between 250 and 300 genetic changes that would cause a gene to stop working normally, and about 50 to 100 genetic variations that have already been associated with an inherited disease. No person carries a perfect set of genes — the fact that everyone has two copies of each gene prevents most of those variations from being problems.
The complete list of genetic variants will give researchers powerful new tools not only for discovering the genetic roots of diseases but for identifying mutations in tumors and other disorders such as heart disease that will respond to specific drugs, theoretically opening a new era of targeted treatments, the researchers said.
In a separate study released online Wednesday by the journal Science, geneticist Evan Eichler of the University of Washington and his colleagues reported that they had found a way to identify multiple copies of genes, a feat which is not achievable by conventional sequencing.
They found that the presence of multiple copies of some genes may be associated with an increased tendency to develop certain diseases. The accumulation of extra copies of genes associated with brain development may have helped humans evolved from lower primates, they found.
Interested in a private Judaic studies instructor — for free? Let us know by clicking here.
Every weekday JewishWorldReview.com publishes inspirational material. Sign up for the daily JWR update. It's free. Just click here.
We want your comments! Please let us know what you think by clicking here.
© 2010, Los Angeles Times Distributed by McClatchy-Tribune Information Services.
|
