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Jonathan Tobin: Defending the Right to a Jewish State

Heather Hale: Compliment your kids without giving them big heads

Megan Shauri: 10 ways you are ruining your own happiness

Carolyn Bigda: 8 Best Dividend Stocks for 2015

Kiplinger's Personal Finance editors: 7 Things You Didn't Know About Paying Off Student Loans

Samantha Olson: The Crucial Mistake 55% Of Parents Are Making At Their Baby's Bedtime

Densie Well, Ph.D., R.D. Open your eyes to yellow vegetables

The Kosher Gourmet by Megan Gordon With its colorful cache of purples and oranges and reds, COLLARD GREEN SLAW is a marvelous mood booster --- not to mention just downright delish
April 18, 2014

Rabbi Yonason Goldson: Clarifying one of the greatest philosophical conundrums in theology

Caroline B. Glick: The disappearance of US will

Megan Wallgren: 10 things I've learned from my teenagers

Lizette Borreli: Green Tea Boosts Brain Power, May Help Treat Dementia

John Ericson: Trying hard to be 'positive' but never succeeding? Blame Your Brain

The Kosher Gourmet by Julie Rothman Almondy, flourless torta del re (Italian king's cake), has royal roots, is simple to make, . . . but devour it because it's simply delicious

April 14, 2014

Rabbi Dr Naftali Brawer: Passover frees us from the tyranny of time

Greg Crosby: Passing Over Religion

Eric Schulzke: First degree: How America really recovered from a murder epidemic

Georgia Lee: When love is not enough: Teaching your kids about the realities of adult relationships

Cameron Huddleston: Freebies for Your Lawn and Garden

Gordon Pape: How you can tell if your financial adviser is setting you up for potential ruin

Dana Dovey: Up to 500,000 people die each year from hepatitis C-related liver disease. New Treatment Has Over 90% Success Rate

Justin Caba: Eating Watermelon Can Help Control High Blood Pressure

The Kosher Gourmet by Joshua E. London and Lou Marmon Don't dare pass over these Pesach picks for Manischewitz!

April 11, 2014

Rabbi Hillel Goldberg: Silence is much more than golden

Caroline B. Glick: Forgetting freedom at Passover

Susan Swann: How to value a child for who he is, not just what he does

Cameron Huddleston: 7 Financial Tasks You Should Tackle Right Now

Sandra Block and Lisa Gerstner: How to Profit From Your Passion

Susan Scutti: A Simple Blood Test Might Soon Diagnose Cancer

Chris Weller: Have A Slow Metabolism? Let Science Speed It Up For You

The Kosher Gourmet by Diane Rossen Worthington Whitefish Terrine: A French take on gefilte fish

April 9, 2014

Jonathan Tobin: Why Did Kerry Lie About Israeli Blame?

Samuel G. Freedman: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Jessica Ivins: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Kim Giles: Asking for help is not weakness

Kathy Kristof and Barbara Hoch Marcus: 7 Great Growth Israeli Stocks

Matthew Mientka: How Beans, Peas, And Chickpeas Cleanse Bad Cholesterol and Lowers Risk of Heart Disease

Sabrina Bachai: 5 At-Home Treatments For Headaches

The Kosher Gourmet by Daniel Neman Have yourself a matzo ball: The secrets bubby never told you and recipes she could have never imagined

April 8, 2014

Lori Nawyn: At Your Wit's End and Back: Finding Peace

Susan B. Garland and Rachel L. Sheedy: Strategies Married Couples Can Use to Boost Benefits

David Muhlbaum: Smart Tax Deductions Non-Itemizers Can Claim

Jill Weisenberger, M.S., R.D.N., C.D.E : Before You Lose Your Mental Edge

Dana Dovey: Coffee Drinkers Rejoice! Your Cup Of Joe Can Prevent Death From Liver Disease

Chris Weller: Electric 'Thinking Cap' Puts Your Brain Power Into High Gear

The Kosher Gourmet by Marlene Parrish A gift of hazelnuts keeps giving --- for a variety of nutty recipes: Entree, side, soup, dessert

April 4, 2014

Rabbi David Gutterman: The Word for Nothing Means Everything

Charles Krauthammer: Kerry's folly, Chapter 3

Amy Peterson: A life of love: How to build lasting relationships with your children

John Ericson: Older Women: Save Your Heart, Prevent Stroke Don't Drink Diet

John Ericson: Why 50 million Americans will still have spring allergies after taking meds

Cameron Huddleston: Best and Worst Buys of April 2014

Stacy Rapacon: Great Mutual Funds for Young Investors

Sarah Boesveld: Teacher keeps promise to mail thousands of former students letters written by their past selves

The Kosher Gourmet by Sharon Thompson Anyone can make a salad, you say. But can they make a great salad? (SECRETS, TESTED TECHNIQUES + 4 RECIPES, INCLUDING DRESSINGS)

April 2, 2014

Paul Greenberg: Death and joy in the spring

Dan Barry: Should South Carolina Jews be forced to maintain this chimney built by Germans serving the Nazis?

Mayra Bitsko: Save me! An alien took over my child's personality

Frank Clayton: Get happy: 20 scientifically proven happiness activities

Susan Scutti: It's Genetic! Obesity and the 'Carb Breakdown' Gene

Lecia Bushak: Why Hand Sanitizer May Actually Harm Your Health

Stacy Rapacon: Great Funds You Can Own for $500 or Less

Cameron Huddleston: 7 Ways to Save on Home Decor

The Kosher Gourmet by Steve Petusevsky Exploring ingredients as edible-stuffed containers (TWO RECIPES + TIPS & TECHINQUES)

Jewish World Review

Method to erase traumatic memories may be on the horizon

By Meredith Cohn




But would doing so make us less human? Ethics confronts science

http://www.JewishWorldReview.com | (MCT) Soldiers haunted by scenes of war and victims scarred by violence may wish they could wipe the memories from their minds. Researchers at the Johns Hopkins University say that may someday be possible.

A commercial drug remains far off — and its use would be subject to many ethical and practical questions. But scientists have laid a foundation with their discovery that proteins can be removed from the brain's fear center to erase memories forever.

"When a traumatic event occurs, it creates a fearful memory that can last a lifetime and have a debilitating effect on a person's life," says Richard L. Huganir, professor and chair of neuroscience in the Hopkins School of Medicine. He said his finding on the molecular process "raises the possibility of manipulating those mechanisms with drugs to enhance behavioral therapy for such conditions as post-traumatic stress disorder."

The research has drawn interest from some involved in mental health care, and some concern.

Kate Farinholt, executive director of the mental health support and information group NAMI Maryland, said many people suffering from a traumatic event might benefit from erasing a memory. But there are a lot of unanswered questions, she said.

"Erasing a memory and then everything bad built on that is an amazing idea, and I can see all sorts of potential," she said. "But completely deleting a memory, assuming it's one memory, is a little scary. How do you remove a memory without removing a whole part of someone's life, and is it best to do that, considering that people grow and learn from their experiences."

Past research already had shown that a specific form of behavior therapy seemed to erase painful memories. But relapse was possible because the memory wasn't necessarily gone.


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By looking at that process, Huganir and postdoctoral fellow Roger L. Clem discovered a "window of vulnerability" when unique receptor proteins are created. The proteins mediate signals traveling within the brain as painful memories are made. Because the proteins are unstable, they can be easily removed with drugs or behavior therapy during the window, ensuring the memory is eliminated.

Researchers used mice to find the window, but believe the process would be the same in humans. They conditioned the rodents with electric shocks to fear a tone. The sound triggered creation of the proteins, called calcium-permeable AMPARS, which formed for a day or two in the fear center, or amygdala, of the mice's brains.

The researchers are working on ways to reopen the window down the road by recalling the painful memory, and using medication to eliminate the protein. That's important because doctors often don't see victims immediately after a traumatic event. PTSD, for example, can surface months later.

Huganir, whose report on erasing fear memories in rodents was published online last month by Science Express, also believes that the window may exist in other centers of learning and may eventually be used to treat pain or drug addiction.

Connie Walker, a Leonardtown, Md., mother of an Iraq war veteran suffering from PTSD, said there isn't enough attention given to the injuries of service members in general and she specifically supports research into PTSD-related therapy. But Walker, a 23-year-Navy veteran herself, said she wouldn't want her son to take a medication to erase what he witnessed.

She said her son began functioning well after he was finally able to get therapy, which she said should be more readily available to every wounded veteran.

"My gut reaction to a drug that erases memories forever is to be frightened," she said. "A person's memory is very much a part of who they are. I recognize we all have some bad memories, though I doubt they can compete with what's coming back from Iraq and Afghanistan. But how can a drug like that be controlled? What else gets eliminated accidentally?"

For now, there aren't yet drugs to erase memories. But there are medications also targeting the amygdala and used with behavior therapy that can lessen the emotional response to painful memories in those with PTSD, such as propranolol, a beta blocker commonly used to treat hypertension.

Paul Root Wolpe, director of the Center for Ethics at Emory University in Atlanta, says permanently erasing memories in humans, if it can be done, wouldn't be a lot different ethically than such behavior modification. Both are memory manipulation. But he said erasing memories is fraught with many more potential pitfalls.

He also said that PTSD sufferers, such as service members in Iraq and Afghanistan, frequently experience more than one traumatic event, and trying to eliminate all the memories could significantly alter a person's personality and history. So could forgetting a whole person after a painful loss or breakup, as depicted in the 2004 movie "Eternal Sunshine of the Spotless Mind."

Wolpe said it can be called dementia when someone forgets that much of their past.

"I don't know what it means to erase that much of a person's life," he said. "You'd leave a giant hole in a person's history. I tend to doubt you'd even be able to."

Further, he said, the safeguards necessary to protect the process from abuse would be difficult. Inmates or soldiers in danger of capture could be subjected to it, for example. Many questions should be decided before testing is pursued in humans, because its use may become "too tempting," he said.

Wolpe could see only limited uses for erasing a memory for now, such as for those suffering after a rape or single terrifying event.

"Certainly, there may be appropriate applications," he said. "But human identity is tied into memory. It creates our distinctive personalities. It's a troublesome idea to begin to be able to manipulate that, even if for the best of motives."

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