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Jewish World Review
Nov. 24, 2008
/ 26 Mar-Cheshvan 5769
Controversy over soaring psychiatric prescriptions for children; Additional controversy over conflicts of interest
By
Michael Arnold Glueck
http://www.JewishWorldReview.com |
Controversy again stirs in the area of psychiatric medications. In this
case the increasing use of new powerful psychotropic medications for
children is being questioned.
This column is not meant to impugn the specialty of psychiatry. Recently
there has been reports of marked advances in research, diagnosis and
treatment of mental illness that will benefit millions of people. This is
the good news and will be the subject of a later commentary.
The controversy discussed here was recently reported in an Association of
American Physicians and Surgeons news release.
A series of articles in the Dallas Morning News focused on alleged financial
conflicts of interest of psychiatrists involved in the Children¹s Medication
Algorithm Project (CMAP). The CMAP protocol has been ³quietly shelved² after
objections were raised by Texas Attorney General Greg Abbott.
The state of Texas is suing a pharmaceutical company that allegedly used
false advertising and improper influence to get its products on the
now-mandatory adult protocol, the Texas Medication Algorithm Project (TMAP).
The newer drugs chosen for the protocol are ten times as expensive than
traditional drugs, but have no substantial advantage, according to a report
by the National Institute of Mental Health.
Sen. Charles Grassley (R-IA) stated that three Harvard experts whose
research contributed to an explosion of antipsychotic drug use in children
failed to report a combined $3.2 million in company consulting fees, in
violation of Harvard¹s rules.
Dr. Graham Emslie of University of Texas Southwestern, on the other hand,
said he had never witnessed improper drug company influence in CMAP
research.
Without the protocol, CMAP advocates warn that Texas children will be
treated by individual doctors who have ³their own personal influences²
(Emily Ramshaw, Dallas Morning News 8/18/08).
Controversy about promotion of psychotropics in children is breaking out in
other states also. New Jersey state assemblyman Michael Coherty wrote to the
state department of health on Aug 20. He inquired about the policy that
permited the NJ Medicaid program to spend $73 million between 2000 and 2007
on antipsychotic drugs for children under the age of 18 -- although the
drugs are not FDA approved for pediatric use. Lawsuits are pending in
several states (Pharmalot.com 9/3/08).
Issues include improper marketing and failure to disclose serious side
effects, which led to state programs to overpay for olanzapine (Zyprexa),
quetiapine (Seroquel), and risperidone (Risperdal).
While slightly fewer people stopped taking atypical antipsychotics Zyprexa
and Seroquel because of tremors compared with older drugs, the new drugs
allegedly gave some of them diabetes. (St. Petersburg Times 4/12/08).
Particularly in children, it is not just the drugs prescribed, but the
diagnoses that are in question. Six million children have been diagnosed
with serious psychiatric disorders warranting drug treatment‹1 million with
bipolar disorder, long believed to occur only in adults (PBS Frontline, The
Medicated Child).
Many children are being identified as potential recipients of psychotropic
drugs through government-supported, school-based mental health ³screening.²
Is this uncovering a vast, previously unrecognized epidemic, as Richard
Friedman, M.D., of the Psychopharmacology Clinic at Weill Cornell Medical
School, holds (N Engl J Med 2006;355:2717-2719)?
A federal court has given the green light to a civil rights lawsuit filed on
behalf of Chelsea Rhoades, who was subjected to TeenScreen without parental
consent, and, like a majority of her classmates, was told she suffered from
mental health problems.
Another ethical concern raised in Texas is the use of psychotropic drugs in
children who are in foster care. Who will speak for these children?
Many physicians will counter by saying the drugs are increasingly used
because they are effective. Teachers report their classrooms would be
unmanageable without some of these medications and there would be no
learning.
All the answers are not in, but the controversy regarding the increasing use
of new, powerful and expensive psychotropic drugs in children deserves
further concern and research. Children are one of the groups that are least
able to speak for themselves.
Every weekday JewishWorldReview.com publishes what many in the media and Washington consider "must-reading". Sign up for the daily JWR update. It's free. Just click here.
Michael Arnold Glueck, M.D., writes on medical, legal and allied social issues in numerous newspapers, magazines and journals locally, nationally and internationally. He is widely quoted in the media.
Comment by clicking here.
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