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April 9, 2014

Jonathan Tobin: Why Did Kerry Lie About Israeli Blame?

Samuel G. Freedman: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Jessica Ivins: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Kim Giles: Asking for help is not weakness

Kathy Kristof and Barbara Hoch Marcus: 7 Great Growth Israeli Stocks

Matthew Mientka: How Beans, Peas, And Chickpeas Cleanse Bad Cholesterol and Lowers Risk of Heart Disease

Sabrina Bachai: 5 At-Home Treatments For Headaches

The Kosher Gourmet by Daniel Neman Have yourself a matzo ball: The secrets bubby never told you and recipes she could have never imagined

April 8, 2014

Lori Nawyn: At Your Wit's End and Back: Finding Peace

Susan B. Garland and Rachel L. Sheedy: Strategies Married Couples Can Use to Boost Benefits

David Muhlbaum: Smart Tax Deductions Non-Itemizers Can Claim

Jill Weisenberger, M.S., R.D.N., C.D.E : Before You Lose Your Mental Edge

Dana Dovey: Coffee Drinkers Rejoice! Your Cup Of Joe Can Prevent Death From Liver Disease

Chris Weller: Electric 'Thinking Cap' Puts Your Brain Power Into High Gear

The Kosher Gourmet by Marlene Parrish A gift of hazelnuts keeps giving --- for a variety of nutty recipes: Entree, side, soup, dessert

April 4, 2014

Rabbi David Gutterman: The Word for Nothing Means Everything

Charles Krauthammer: Kerry's folly, Chapter 3

Amy Peterson: A life of love: How to build lasting relationships with your children

John Ericson: Older Women: Save Your Heart, Prevent Stroke Don't Drink Diet

John Ericson: Why 50 million Americans will still have spring allergies after taking meds

Cameron Huddleston: Best and Worst Buys of April 2014

Stacy Rapacon: Great Mutual Funds for Young Investors

Sarah Boesveld: Teacher keeps promise to mail thousands of former students letters written by their past selves

The Kosher Gourmet by Sharon Thompson Anyone can make a salad, you say. But can they make a great salad? (SECRETS, TESTED TECHNIQUES + 4 RECIPES, INCLUDING DRESSINGS)

April 2, 2014

Paul Greenberg: Death and joy in the spring

Dan Barry: Should South Carolina Jews be forced to maintain this chimney built by Germans serving the Nazis?

Mayra Bitsko: Save me! An alien took over my child's personality

Frank Clayton: Get happy: 20 scientifically proven happiness activities

Susan Scutti: It's Genetic! Obesity and the 'Carb Breakdown' Gene

Lecia Bushak: Why Hand Sanitizer May Actually Harm Your Health

Stacy Rapacon: Great Funds You Can Own for $500 or Less

Cameron Huddleston: 7 Ways to Save on Home Decor

The Kosher Gourmet by Steve Petusevsky Exploring ingredients as edible-stuffed containers (TWO RECIPES + TIPS & TECHINQUES)

Jewish World Review

Researchers look to ancient remedy to fight side effects of chemotherapy

By William Weir


http://www.JewishWorldReview.com | (MCT) Yale researchers have developed a medication based on a Chinese herbal recipe more than 1,800 years old to counteract the adverse effects of chemotherapy.

The medicine, called PHY906, would relieve the gastrointestinal side effects of a common chemotherapy drug known as CPT-11, but not the drug's effectiveness in fighting cancer cells. Lead researcher Yung-Chi Cheng, a professor of pharmacology at Yale, calls the medication "a marriage of Western and Eastern approaches to the treatment of cancer."

CPT-11 (also known as Irinotecan) is commonly prescribed with other chemotherapy agents. Its side effects cause a number of gastrointestinal ailments and are often treated with several different medications, with mixed results. The PHY906, the researchers say, tackled multiple side effects partly by reducing inflammation and creating new intestinal cells.

The medication was tested on mice that were undergoing chemotherapy. Those that were administered PHY906 showed less weight loss and more anti-tumor activity. Not only did it not compromise the chemotherapy medication's effectiveness, the researchers noted, it enhanced it.

"Herbal medicines, composed of multiple biologically active compounds, are widely claimed to help a variety of diseases," the researchers write in the paper, which was published Wednesday in the journal Science Translational Medicine. "However, they have not been fully accepted by mainstream medicine because of the complex nature of the formulae, as well as a lack of stringent quality control."

It is derived from a recipe of four plants called Huang Qin Tang, which was first described in Chinese medical literature about 1,800 years. Still used today, it is given to treat such gastrointestinal symptoms as diarrhea, nausea and vomiting. The researchers say the method they've developed allows for the formula to be prepared to exact standards.

Cheng, who is also the co-chairman of the Consortium for the Globalization of Chinese Medicine, has spent several years incorporating traditional Chinese remedies into modern medicine. He's not the only one. A paper published in the June issue of Evidence-based Complementary and Alternative Medicine noted that there has been an increased effort to find new medications based on Chinese herbal remedies to counteract the side effects of synthetic drugs.

Cheng developed the drug for the New Haven, Conn.-based pharmaceutical developer PhytoCeutica, which he co-founded.

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