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May 25, 2012
Mark Clayton: Is Hillary's State Dept. hacking Al Qaeda? Not quite
Erika Bolstad: Temple cancels Wasserman Schultz speech
The Kosher Gourmet by Ethel G. Hofman: The former president of the International Association of Culinary Professionals, whose members included the likes of Julia Child, is back with contemporary Shavous cuisine: Ruby Fruit Soup, Sweet Noodle Kugel with Cheese, Key Lime Curd, Calsone Casserole Frittata with Wild Mushrooms, Sun-dried tomatoes and Olives, Baked Tilapia with Pepper Cheese Cream and Brown Sugar Shortbread
May 24, 2012
Jeff Jacoby: The peace process battered Israel's reputation
Michael Muskal: 'Pro-choice' position hits record low, according to poll
Chris Farrell: Are We in a Tech Bubble?
The Kosher Gourmet by Penelope Wall: PHILLY CHEESE STEAKS --- hold the steak!
May 23, 2012
Tony Pugh: More private colleges offering tuition discounts
Mary Beth Franklin: How to Choose the Right Annuity for You
Tina Susman: The wig wasn't enough: Man gets 13 years for posing as his dead mom
The Kosher Gourmet by Emma Christensen:A simple way to do fish right
May 22, 2012
Warren Richey: Can US group challenge overseas surveillance act? Supreme Court to decide
Thomas M. Anderson: Walking Away From a Mortgage
The Kosher Gourmet by Megan Gordon: Enjoy a celebration of the most rich and layered flavors: Black bean, sweet potato and quinoa chili
May 21, 2012
Mark Clayton: Cybersecurity: How US utilities passed up chance to protect their networks
Howard LaFranchi: NATO summit: Who will foot the bill for long-term Afghanistan security?
Chris Farrell : Earn Dividends in Emerging Markets with This WisdomTree ETF
Stephen Whiteside, Ph.D. : Mayo Clinic Medical Edge: Social anxiety disorder --- or just shy?
Guy Jackson : Victim's father regrets death of Lockerbie bomber
The Kosher Gourmet by Mario Batali: Famed chef's veal shoulder farsumagru: A festive meat course for late spring
May 18, 2012
Rabbi Berel Wein: Striving: The People of the Book's Book for (All of) the People
Steven Goldberg: 5 Great Stock Picks and the Exchange-Traded Fund that Owns Them
Mary Pickett, M.D.: Ask the Harvard Experts: Don't be forced into gluten-free lifestyle based merely on a doctor's false-positive test
The Kosher Gourmet by Carolyn Malcoun: DIY healthy lunchbox treats: HOMEMADE FRUIT BARS for kids and brown-bagging adults alike
May 17, 2012
Warren Richey: Teacher fired for being unwed and pregnant can sue religious school, court rules
Josh Mitnick: Netanyahu's 'centrist' coalition is already proving it's anything but
Steven Goldberg: Earn Dividends in Emerging Markets with This WisdomTree ETF
Amina Khan: Research links coffee to lower death rates
The Kosher Gourmet by Faith Duran : Cheesy Potato Breakfast Casserole with Cheddar and Sun-Dried Tomatoes
May 16, 2012
Carmen Terzic, M.D., Ph.D. : Mayo Clinic Medical Edge: A variety of exercises can help improve balance
Melissa Healy: National strategy on Alzheimer's disease aims to halt it by 2025
The Kosher Gourmet by Joyce White : GOODNESS GRACIOUS: GREENS! 4 winning recipes that are no longer just for down-home folks (Includes expert tips & techniques)
May 15, 2012
Kristen Chick: Obama administration resumes arms sales to Bahrain despite serious unresolved human rights issues. Activists feel abandoned
Pat Mertz Esswein: Homes are now affordable again and mortgage rates are low. What you need to know before you buy
Kathy Kristof: Our Practical Investor Fights Inflation with These 6 Investments
Sue Hubbard, M.D.: The Kid's Doctor: Lactose intolerant young child? Check again
The Kosher Gourmet by Kathy Hunt: Spread a Little Excitement with EXOTIC CONDIMENTS (4 RECIPES)
May 14, 2012
Lisa Gerstner: How to Protect Your Identity, Finances If You Lose Your Phone
Harvard Health Letters: Heart disease and dementia
The Kosher Gourmet by Megan Gordon: MANGO COCONUT OAT MORNING MUFFINS are a bright but hearty delight
May 11, 2012
Jessica L. Anderson: Get the Best Deal on a Used Car
Jett Stone: Forget face-lifts and fake knees. Scientists have seen the fountain of youth --- and it's broccoli
The Kosher Gourmet by Chef Mario Batali: The famed chef's vegetable dish that tastes true to the season: FAVAS AND SUGAR SNAP PEAS WITH POTATOES AND TARRAGON
May 10, 2012
Sergei L. Loiko: Putin sends warning to U.S., NATO in Victory Day speech at Red Square
Mary Rourke: How being a 'mentch' got Vidal Sasoon his start and fighting in Israel's War of Independence provided him with confidence and a strong sense of his own identity
Jeff Bertolucci: Get Home Phone Service for Less Than $10 a Month
The Kosher Gourmet by Betty Rosbottom: Gleaming with its golden, crimson, and snowy white hues, this silken smooth and creamy STRAWBERRY ORANGE TRIFLE looks impressive, but is easy to prepare
May 9, 2012
Sharon Palmer, R.D. How you can reduce your risk -- or delay -- chronic diseases associated with aging
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Jewish World Review
Researchers unveil detailed look at genetic causes of autism
By
Mark Johnson
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http://www.JewishWorldReview.com | (MCT)
An international team of researchers unveiled the most detailed picture yet of the genetic causes of autism, identifying specific genes and pathways that play a role in the complex disorder, and that can now be targeted by drug companies hoping to provide treatment for millions worldwide.
The scientists compared the DNA of almost 1,000 people with autism with DNA from almost 1,300 people who do not have the disorder. The findings, described Wednesday in the journal Nature, show that the collection of developmental disabilities known as autism spectrum disorder involve dozens of genes and numerous combinations of rare mutations so many that patients may each have a unique form.
So, while the new research could enable some families to receive more precise genetic counseling about risks, most will not get definitive answers. Scientists involved in the study said not enough is known yet to suggest prenatal testing for autism.
Anthony Monaco, an Oxford University researcher and one of more than 100 authors of the Nature paper, compared the effort to understand autism to "trying to put together a very large jigsaw puzzle without the benefit of a nice colorful picture on the box." He said the pieces discovered in the new study resemble the puzzle's frame.
Studies have shown autism rates to be increasing it is currently found in about one out of every 110 births but the new paper does not shed light on possible explanations for the rise. Scientists believe that in addition to the genetic causes, there are also environmental factors that play a role.
Despite the caveats, the new genetic analysis by scientists in Canada, the U.S., Britain and other countries could help doctors diagnose children earlier. Although children often begin showing symptoms before age 3, some are not diagnosed until age 5. Symptoms differ but many children with autism become withdrawn. Some lose language skills. Some become aggressive.
"There is no autism medication," said Emily Levine, executive director of the Autism Society of Southeastern Wisconsin. "There are some medications that help with some symptoms in some people."
Authors of the new paper said the complexity and variation they found examining the genetic underpinnings of autism should not prevent pharmaceutical companies from developing treatments in the future. Many of the genes they identified are involved in pathways that determine how synapses grow and communicate with each other. Synapses allow neurons to pass chemical or electrical signals.
David Bick, medical director of genetics at Children's Hospital of Wisconsin, said the pathways cited in the paper can be thought of as complex Rube Goldberg machines, in which proteins direct a cascade of actions. The problems caused by autism may occur because the chain of actions is somehow interrupted when a single protein does not work.
Identifying these pathways may allow drug companies to develop ways of stimulating a broken protein or bypassing a trouble spot altogether, said Bick, a professor of pediatrics at the Medical College of Wisconsin who wasn't involved in the research.
Scientists used equipment called DNA micro-arrays to scan thousands of specific locations in the genome, or genetic blueprint. The method is more targeted than sequencing the entire genome, which spans 3 billion locations.
The international team examining autism looked for segments of DNA that are either copied or deleted, and found numerous different examples. The most common of these segments were still very rare, showing up in less than 1 percent of the people with autism in the study.
"What is important about this paper is that it says rare changes in a whole variety of genes are a good place to look for autism," said Bick said.
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