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December 2, 2014

Jonathan Tobin: Defending the Right to a Jewish State

Heather Hale: Compliment your kids without giving them big heads

Megan Shauri: 10 ways you are ruining your own happiness

Carolyn Bigda: 8 Best Dividend Stocks for 2015

Kiplinger's Personal Finance editors: 7 Things You Didn't Know About Paying Off Student Loans

Samantha Olson: The Crucial Mistake 55% Of Parents Are Making At Their Baby's Bedtime

Densie Well, Ph.D., R.D. Open your eyes to yellow vegetables

The Kosher Gourmet by Megan Gordon With its colorful cache of purples and oranges and reds, COLLARD GREEN SLAW is a marvelous mood booster --- not to mention just downright delish
April 18, 2014

Rabbi Yonason Goldson: Clarifying one of the greatest philosophical conundrums in theology

Caroline B. Glick: The disappearance of US will

Megan Wallgren: 10 things I've learned from my teenagers

Lizette Borreli: Green Tea Boosts Brain Power, May Help Treat Dementia

John Ericson: Trying hard to be 'positive' but never succeeding? Blame Your Brain

The Kosher Gourmet by Julie Rothman Almondy, flourless torta del re (Italian king's cake), has royal roots, is simple to make, . . . but devour it because it's simply delicious

April 14, 2014

Rabbi Dr Naftali Brawer: Passover frees us from the tyranny of time

Greg Crosby: Passing Over Religion

Eric Schulzke: First degree: How America really recovered from a murder epidemic

Georgia Lee: When love is not enough: Teaching your kids about the realities of adult relationships

Cameron Huddleston: Freebies for Your Lawn and Garden

Gordon Pape: How you can tell if your financial adviser is setting you up for potential ruin

Dana Dovey: Up to 500,000 people die each year from hepatitis C-related liver disease. New Treatment Has Over 90% Success Rate

Justin Caba: Eating Watermelon Can Help Control High Blood Pressure

The Kosher Gourmet by Joshua E. London and Lou Marmon Don't dare pass over these Pesach picks for Manischewitz!

April 11, 2014

Rabbi Hillel Goldberg: Silence is much more than golden

Caroline B. Glick: Forgetting freedom at Passover

Susan Swann: How to value a child for who he is, not just what he does

Cameron Huddleston: 7 Financial Tasks You Should Tackle Right Now

Sandra Block and Lisa Gerstner: How to Profit From Your Passion

Susan Scutti: A Simple Blood Test Might Soon Diagnose Cancer

Chris Weller: Have A Slow Metabolism? Let Science Speed It Up For You

The Kosher Gourmet by Diane Rossen Worthington Whitefish Terrine: A French take on gefilte fish

April 9, 2014

Jonathan Tobin: Why Did Kerry Lie About Israeli Blame?

Samuel G. Freedman: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Jessica Ivins: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Kim Giles: Asking for help is not weakness

Kathy Kristof and Barbara Hoch Marcus: 7 Great Growth Israeli Stocks

Matthew Mientka: How Beans, Peas, And Chickpeas Cleanse Bad Cholesterol and Lowers Risk of Heart Disease

Sabrina Bachai: 5 At-Home Treatments For Headaches

The Kosher Gourmet by Daniel Neman Have yourself a matzo ball: The secrets bubby never told you and recipes she could have never imagined

April 8, 2014

Lori Nawyn: At Your Wit's End and Back: Finding Peace

Susan B. Garland and Rachel L. Sheedy: Strategies Married Couples Can Use to Boost Benefits

David Muhlbaum: Smart Tax Deductions Non-Itemizers Can Claim

Jill Weisenberger, M.S., R.D.N., C.D.E : Before You Lose Your Mental Edge

Dana Dovey: Coffee Drinkers Rejoice! Your Cup Of Joe Can Prevent Death From Liver Disease

Chris Weller: Electric 'Thinking Cap' Puts Your Brain Power Into High Gear

The Kosher Gourmet by Marlene Parrish A gift of hazelnuts keeps giving --- for a variety of nutty recipes: Entree, side, soup, dessert

April 4, 2014

Rabbi David Gutterman: The Word for Nothing Means Everything

Charles Krauthammer: Kerry's folly, Chapter 3

Amy Peterson: A life of love: How to build lasting relationships with your children

John Ericson: Older Women: Save Your Heart, Prevent Stroke Don't Drink Diet

John Ericson: Why 50 million Americans will still have spring allergies after taking meds

Cameron Huddleston: Best and Worst Buys of April 2014

Stacy Rapacon: Great Mutual Funds for Young Investors

Sarah Boesveld: Teacher keeps promise to mail thousands of former students letters written by their past selves

The Kosher Gourmet by Sharon Thompson Anyone can make a salad, you say. But can they make a great salad? (SECRETS, TESTED TECHNIQUES + 4 RECIPES, INCLUDING DRESSINGS)

April 2, 2014

Paul Greenberg: Death and joy in the spring

Dan Barry: Should South Carolina Jews be forced to maintain this chimney built by Germans serving the Nazis?

Mayra Bitsko: Save me! An alien took over my child's personality

Frank Clayton: Get happy: 20 scientifically proven happiness activities

Susan Scutti: It's Genetic! Obesity and the 'Carb Breakdown' Gene

Lecia Bushak: Why Hand Sanitizer May Actually Harm Your Health

Stacy Rapacon: Great Funds You Can Own for $500 or Less

Cameron Huddleston: 7 Ways to Save on Home Decor

The Kosher Gourmet by Steve Petusevsky Exploring ingredients as edible-stuffed containers (TWO RECIPES + TIPS & TECHINQUES)

Jewish World Review

Pot in a pill: All the pain relief without the smoke

By Melissa Healy



Up in smoke goes the debate about medical marijuana


JewishWorldReview.com | (MCT) Unless there is some recognized analgesic effect of rolling a joint, lighting it up and deeply inhaling the by-products of marijuana combustion, then it stands to reason that you could distill the psychoactive ingredient of marijuana, tetrahydrocannabinol, and formulate it into, say, a capsule. Doing so would combine the relief that comes with smoked marijuana with the ease of a pill and the quality control that comes with approval by the Food and Drug Administration.

Up in smoke goes the debate about medical marijuana.

Let me introduce you to dronabinol. It turns out that the miracle that is modern psychopharmacology has now shown it IS possible to render pot's analgesic effects into capsule form. And according to a new study, it works just as well as smoked marijuana at tamping down pain. But the capsule's effects last longer, and they come with fewer of the "abuse-related subjected effects" (i.e., feeling high) than does smoked marijuana.


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For the record, dronabinol did induce some of smoked marijuana's other side effects, some of which have medicinal value to certain populations: It did increase appetite, decrease nausea and improve sleep.

The new research appeared Monday in the Nature journal Neuropsychopharmacology. It was authored by a group from Columbia University's College of Physicians and Surgeons.

In a small, preliminary study, researchers ran 30 subjects — all of them regular pot smokers who were in good health — through five experimental sessions. In each session, the subject would plunge his or her left hand into a vat of water set to a temperature just above freezing — 39 degrees — and hold it there for as long as was tolerable (up to two minutes), and then answer questions about the intensity of the pain or discomfort they felt.

This procedure followed the administration of one of the following: three to seven puffs of a marijuana cigarette in one of two strengths (provided by the National Institute on Drug Abuse); a single capsule containing dronabinol in one of two doses, high and low; or a capsule containing placebo medication.

Each subject served as his or her own comparison group across the drug conditions. And after each dose, subjects answered questions about their "liking" for the drug administered and other subjective feelings that might suggest the degree to which the drug would inspire drug-seeking behavior.

Both marijuana and dronabinol at the higher dose increased pain tolerance and decreased pain sensitivity roughly equally in subjects. Compared with smoked marijuana, it took a bit longer for dronabinol's analgesic effects to peak — about 180 minutes for the higher-dose THC capsule, compared with about 15 minutes for smoked marijuana. But for dronabinol, there was substantial pain relief during the period leading up to that peak; after smoked marijuana reached its peak pain-killing effect, the analgesia it brought dropped off quickly.

Subjects declared themselves to feel less "high" on both doses of dronabinol than on marijuana.

Conclusions: marijuana in a capsule seems to fight pain, at least in a population of people who already use marijuana regularly and don't have chronic or neuropathic pain. Its effects on populations of patients who don't usually smoke pot, and whose pain comes from disease states such as cancer or neuropathy, still need to be tested.

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© 2013, Los Angeles Times Distributed by MCT Information Services



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